Publications

Preprints

Arribas Perez M., Moriones O.H., Bastús N.G., Puntes V., Nelson A., Beales P.A.; Isolated occurrences of membrane perturbation by mechanosensing from weakly aggregating silver nanoparticles. bioRxiv (2019). doi.org/10.1101/623678. [link]

Khan S., McCabe J., Hill K. and Beales P.A.; Biodegradable Hybrid Block Copolymer – Lipid Vesicles as Potential Drug Delivery Systems. ChemRxiv (2019). [link]

2019

Booth A., Marklew C.J., Ciani B. and Beales P.A.; In vitro membrane remodelling by ESCRT is regulated by negative feedback from membrane tension. iScience 15, 173-184 (2019). [link]

Chand S., Beales P.A., Claeyssens F. and Ciani B.; Topography design in model membranes: Where biology meets physics. Experimental Biology and Medicine 244, 294-303 (2019). [link]

Jones S.J., Taylor A.F. and Beales P.A.; Towards feedback-controlled nanomedicines for smart, adaptive delivery. Experimental Biology and Medicine 244, 283-293 (2019). [link]

2018

Marklew C.J., Booth A., Beales P.A. and Ciani B.; Membrane remodelling by a lipidated endosomal sorting complex required for transport-IIIchimera, in vitro. Interface Focus 8, 20180035 (2018). [link]

Beales P.A., Ciani B. and Mann S.; The artificial cell: biology-inspired compartmentalization of chemical function. Interface Focus 8, 20180046 (2018). [link]

Werner M., Auth T., Beales P.A., Fleury J.B., Hook F., Kress H., van Lehn R.C., Muller M., Petrov E.P., Sarkisov L., Sommer J.U. and Baulin V.A.; Nanomaterial interactions with biomembranes: Bridging the gap between soft matter models and biological context. Biointerphases 13 (2), 028501 (2018). [link]

Seneviratne R., Khan S., Moscrop E., Rappolt M., Muench S.P., Jeuken L.J.C. and Beales P.A.; A reconstitution method for integral membrane proteins in hybrid lipid-polymer vesicles for enhanced functional durability. Methods 147, 142 – 149 (2018) [link]

2017

Beales P.A.; Biophysics: A toehold in cell surface dynamics. Nature Nanotechnology 12, 404-406 (2017). [link]

Beales P.A., Khan S., Muench S.P. and Jeuken L.J.C.; Durable vesicles for reconstitution of membrane proteins in biotechnology. Biochem. Soc. Trans. 45(1), 15-26 (2017). [link]

2016

Khan S., Li M., Muench S.P., Jeuken L.J.C. and Beales P.A.; Durable Proteo-Hybrid Vesicles for the Extended Functional Lifetime of Membrane Proteins in Bionanotechnology. Chem. Commun. 52, 11020 – 11023 (2016) [link]

Petrache A.I., Machin D.C., Williamson D.J., Webb M.E. and Beales P.A.; Sortase-mediated labelling of lipid nanodiscs for cellular tracing. Mol. BioSyst. 12, 1760 – 1763 (2016). [link]

Miles D.E., Mitchell E.A., Kapur N., Beales P.A. and Wilcox R.K.; Peptide-Glycosaminoglycan hybrid hydrogels as an injectable intervention for spinal disc degeneration. J. Mater. Chem. B 4, 3225 – 3231 (2016).  [link]

2015

PCCP, Physical Chemistry Chemical Physics, 2015Bueno Leite N., Aufderhorst-Roberts A., Palma M.S., Connell S.D., Ruggiero Neto J. and Beales P.A.; PE and PS Lipids Synergistically Enhance Membrane Poration by a Peptide with Anticancer Properties. Biophys. J. 109 (5), 936 – 947 (2015). [link]

Beales P.A. and Ciani B.; Chemical compartmentalisation by membranes: from biological mechanism to biomimetic applications. Phys. Chem. Chem. Phys. 17, 15487 – 15488 (2015). [link]

Beales P.A., Ciani B. and Cleasby A.; Nature’s lessons in design: nanomachines to scaffold, remodel and shape membrane compartments. Phys. Chem. Chem. Phys. 17, 15489 – 15507 (2015). [link]

2014

Advances in Planar Lipid Bilayers and LiposomesGoodchild S.C., Sheynis T., Thompson R., Tipping K.W., Xue W.-F., Ranson N.A., Beales P.A., Hewitt E.W. and Radford S.E.; β2-Microglobulin Amyloid Fibril-Induced Membrane Disruption is Enhanced by Endosomal Lipids and Acidic pH. PLoS ONE 9 (8), e104492 (2014). [link]

Gordon V.D., Beales P.A., Shearman G.C., Zhao Z., Seddon J.M., Poon W.C.K. and Egelhaaf S.U.; Solid-like Domains in Mixed Lipid Bilayers: Effect of Membrane Lamellarity and Transition Pathway. Advances in Planar Lipid Bilayers and Liposomes, 20, 137 – 154 (2014). [link]

Beales P.A. and Vanderlick T.K.; Application of nucleic acid – lipid conjugates for the programmable organisation of liposomal modules. Adv. Colloid Interface Sci. 207, 290 – 305  (2014). [link]

2013

Geerts N., Schreck C.F., Beales P.A., Shigematsu H., O’Hern C.S. and Vanderlick T.K.; Using DNA-driven assembled phospholipid nanodiscs as a scaffold for gold nanoparticle patterning. Langmuir 29 (42), 13089 – 13094 (2013). [link]

Xu J., Vanderlick T.K. and Beales P.A.; Lytic and Non-Lytic Permeabilization of Cardiolipin-Containing Lipid Bilayers Induced by Cytochrome c. PLoS ONE 8 (7), e69492 (2013). [link]

Bergstrom C.L., Beales P.A., Yang L., Vanderlick T.K. and Groves J.T.; Cytochrome c causes pore formation in cardiolipin-containing membranes. Proc. Natl. Acad. Sci. USA 110 (16), 6269 – 6274 (2013). [link]

Churchman A.H., Wallace R., Milne S.J., Brown A.P., Brydson R. and Beales P.A.; Serum Albumin enhances the Biomembrane Activity of ZnO Nanoparticles. Chem. Commun. 49 (39), 4172 – 4174 (2013). [link]

Beales P.A., Geerts N., Inampudi K.K., Shigematsu H., Wilson C.J. and Vanderlick T.K.; Reversible assembly of stacked membrane nanodiscs with reduced dimensionality and variable periodicity. J. Am. Chem. Soc. 135 (9), 3335–3338 (2013). [link]

2012

Langmuir, 2012Zhang S., Nelson L.A. and Beales P.A.; Freezing or wrapping, the role of particle size behind the mechanism of nanoparticle – biomembrane interaction. Langmuir 28 (35), 12831-12837 (2012). [link]

Nam J., Vanderlick T.K. and Beales P.A.; Formation and dissolution of phospholipid domains with varying textures in hybrid lipo-polymersomes. Soft Matter 8, 7982-7988 (2012). [link]

2011

Beales P.A., Bergstrom C.L., Groves J.T. and Vanderlick T.K., Single Vesicle Observations of the Cardiolipin – Cytochrome c Interaction: Induction of Membrane Morphology Changes. Langmuir 27 (10), 6107-6115 (2011). [link]

Beales P.A., Nam J. and Vanderlick T.K.; Specific Adhesion between DNA-functionalized “Janus” Vesicles: Size-Limited Clusters. Soft Matter 7 (5), 1747 – 1755 (2011). [link]

Nam J., Beales P.A. and Vanderlick T.K.; Giant Phospholipid/Block Copolymer Hybrid Vesicles: Mixing Behavior and Domain Formation. Langmuir 27 (1), 1-6 (2011). [link]

2000 – 2010

Beales P.A. and Vanderlick T.K.; Partitioning of Membrane-Anchored DNA Between Coexisting Lipid Phases. J. Phys. Chem. B. 113 (42), 13678 – 13686 (2009). [link]

Beales P.A. and Vanderlick T.K.; DNA as Membrane-Bound Ligand-Receptor Pairs: Duplex Stability is Tuned by Intermembrane Forces. Biophys.J. 96 (4), 1554 – 1565 (2009). [link]

Beales P.A. and Vanderlick T.K.; Specific Binding of Different Vesicle Populations by the Hybridization of Membrane-Anchored DNA. J. Phys. Chem. A 111 (49), 12372 – 12380 (2007). [link]

Gordon V.D., Beales P.A., Zhao Z., Blake C., Mackintosh F.C., Olmsted P.D., Cates M.E., Egelhaaf S.U. and Poon W.C.K.; Lipid organization and the morphology of solid-like domains in phase-separating binary lipid membranes; J. Phys.: condens. matter 18 (32), L415 – L420 (2006). [link]

Beales P.A., Gordon V.D., Zhao Z., Egelhaaf S.U. and Poon W.C.K.; Solid-like domains in fluid membranes; J. Phys.: condens. matter 17 (45), S3341 – S3346 (2005). [link]

Poon W.C.K., Egelhaaf S.U., Beales P.A., Salonen A. and Sawyer L.; Protein crystallisation: scaling of charge and salt concentration in lysozyme solutions; J. Phys.: condens. matter 12 (35), L569 – L574 (2000). [link]